Monday, March 3, 2008

New target for prostate cancer treatment

Researchers have successfully killed prostate cancer cells by targeting a protein that is critical for the cancer's spread.

The finding is significant because it would give doctors another tool to battle advanced prostate cancers that are resistant to hormone therapy.

Scientists at Kimmel Cancer Center in Philadelphia killed cancer cells in the laboratory cell cultures and experimental animals by blocking Stat5, a protein that keeps the cancer cells healthy.

The researchers blocked the protein in a number of different ways, all of which were successful in killing the cancer cells.

The team was headed by Marja Nevalainen, M.D., Ph.D., associate professor of Cancer Biology at Jefferson Medical College of Thomas Jefferson University, determined that the Stat5 protein was "switched on" in nearly all recurrent prostate cancers.

More details at Science Daily or Thomas Jefferson University.

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